Setup requires plugin the device to PC/mac , register to logitech, enter brand and model then click save to device. You will need to remember the input settings in like HDMI1 on TV etc to set up activities and once you know this it didn't take long to create the activities.
One of the best gadgets I own; Not only replaces 4 remotes but also allows you to set up activities - one touch turns on the devices in right order
None as yet