I am an extremely satisfied user of Canon 400 mm F 5.6 EFL lens. I have used this lens with variopus Canon bodies like Canon EOS 1RS, EOS 1N, EOS 3, EOS 1DS mark II, EOS 5D. I have had wonderful experience with all these bodies with excellent sharpness in the center of the frame.
Outstanding sharpness; well controlled flare characteristics; very little lateral colour; Minimal drop in sharpness with the 1.4 X EF teleconverter
lack of USM; I guess that is about it