Plenty of room to work with. This case is very well built, no cheap thin metal! Descent air flow. The Cooler Master Nepton 240M CPU Water Cooling System, All-In-One Kit with 240mm Radiator and 2 Silencio Fans RL-N24M-24PK-R2 was a tight fit. I wound up using a corsair H-60 water cooler.