Gearbox took the trend of mashing together multiple genres and has put its cherry on top. The new shooter/RPG/MMO takes what others have done, refines it, throws in a slew of concepts and comes out smelling like a rose.
...You really got into Fallout 3 ; ...You've wanted to play World of Warcraft without all those elves and swords; ...You get a contact high from loot games
...There's never a good reason to open up the menus; ...You prefer to keep your genres separate; ...You prefer not to grind for levels