I bought this mouse 2 weeks ago. Fits perfectly with a palm hold, no fatigue at all unlike many other mice I've tried. I have medium sized hands (can palm a basketball). The weight is excellent at 104grams and the lift off distance on the optical sensor makes you feel you are using a stable, natural feeling mouse rather than many other mice which leaves much to be desired (too snappy, etc). Perfect for someone who wants a reliable daily driver.